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Unstable Personality Disorder | West Coast Cannabis Canada
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Emotionally Unstable Personality Disorder (EUPD), often referred to as Borderline Personality Disorder (BPD), impacts social interactions, emotional stability, and can result in impulsive or self-harming behaviors. Treatment can be expensive, with success rates ranging from 35% to 50%. Researchers are investigating alternative treatments to support traditional therapies.

A promising addition to EUPD treatment involves using cannabis, commonly known as weed. It is budget-friendly, and its components can provide benefits for patients with EUPD. Those unable to afford multiple treatments may consider West Coast Cannabis Canada for affordable cannabis options.

Key Takeaways:

  • Participants with EUPD using THC or high CBD experience positive results in managing their symptoms.
  • High doses of CBD (800 mg/day) and THC flower treatment can elevate circulating levels of anandamide.
  • Dysfunction in the endocannabinoid system, responsible for regulating emotions and stress, contributes to Emotionally Unstable Personality Disorder.

Emotionally Unstable Personality Disorder or Borderline Personality Disorder

EUPD is a mental health condition affecting self-perception and relationships, leading to challenges in daily life. It is characterized by intense, unstable relationships, impulsivity, and a distorted self-image.

While the exact causes remain unclear, genetics, trauma, and neurotransmitter imbalances may play a role. Dysfunction in the endocannabinoid system, which regulates emotion and stress, may exacerbate EUPD symptoms.

EUPD Treatment

Despite guidelines indicating no effective drugs for EUPD, clinicians sometimes prescribe medications like antipsychotics and antidepressants.

Antipsychotic and sedative medications can be beneficial for short-term crisis management or treating coexisting conditions. A significant percentage of EUPD patients—up to 90% in some reports—take at least one cannabis, including antipsychotics, antidepressants, mood stabilizers, and sedatives.

Polypharmacy is prevalent among these patients. Many of these medications carry side effects and are used off-label for EUPD. Although some medications may alleviate specific symptoms, they do not alter the overall prognosis of the condition.

Cannabis-Based Medicine for EUPD (CBM)

Cannabis-based medicines are derived from the cannabis plant and contain cannabinoids, the active compounds found within, such as tetrahydrocannabinol (THC) and cannabidiol (CBD). These medicines address medical conditions and symptoms, including pain, inflammation, anxiety, seizures, and more.

Numerous studies are elaborating on the effects of cannabis on mental health. For instance, research published in Frontiers in Psychiatry indicates that marijuana can improve depression and enhance sleep quality and overall life quality. These findings provide strong justification for further studies into marijuana’s effects on various mental illnesses.

CBM for Unstable Personality Disorder

A narrative review and case series study conducted in 2022 showcased the use of cannabinoids for managing EUPD symptoms in seven patients. Researchers examined the cellular and molecular mechanisms and reviewed current evidence for cannabis-based medicinal products (CBMP) as a potential EUPD treatment.

Materials and Methods

Participants diagnosed with EUPD who had tried at least one medication and one form of psychotherapy and had at least one follow-up review at a Zerenia clinic, with patient-reported outcome measures (PROMS) records.

CBM used included dried flower for inhalation (20-60g per month) and oral extracts with THC (9-10mg/day) and CBD (40mg/day). Formulations included high THC, low CBD, balanced THC and CBD, and high CBD, low THC.

Measurement involved Clinical Global Impression Improvement (CGI-I) Scale and Patient’s Global Impression of Change (PGIC) Scale.

Researchers personalized dosing through slow titration and provided guidelines for increasing doses until satisfactory symptom control was achieved or side effects were observed.

Results

At a one-month follow-up, six participants reported improvements, with five rating their progress as a six on the PGIC scale. Only one patient, who received a chemotype 2 oral extract, reported no benefit, suggesting that inhaled THC or higher oral CBD doses may be more effective.

All participants tolerated the treatment well, with no side effects reported, which is crucial for adherence. Younger patients may feel more comfortable with cannabis despite societal stigma.

Hypothesis

Researchers propose that exogenous cannabinoids may help restore the tonic activation of the endocannabinoid system (ECS) in the central nervous system (CNS). THC activates presynaptic CB1 receptors, and both cannabinoids bind to fatty-acid binding proteins (FABPs), potentially slowing down the deactivation of anandamide.

High doses of oral CBD (800 mg/day) and patients treated with chemotype 1 flower exhibited higher levels of anandamide in circulation. It remains uncertain whether this is due to CBD affecting anandamide transport or degradation or if it interacts with other molecular targets. In contrast, psychiatric medications typically require 2-3 weeks for initial effects, with longer durations for remission.

Rapid symptom relief can be crucial during an “EUPD crisis,” when distressed patients may resort to benzodiazepines and other anxiety medications, which can result in rapid tolerance and dependence.

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Manage Changes in Behaviour with Bulk Cannabis Via Mail-Order Marijuana Service

Cannabinoids are effective in managing unstable personality disorders by targeting the ECS to maintain balance in anandamide breakdown. Patients with EUPD can benefit from West Coast Cannabis Canada for affordable cannabis options to help manage their symptoms.

An online cannabis store with same-day delivery or mail-order options provides a balance of quality and affordability. Enjoy exceptional customer service and explore a wide range of bulk cannabis strains, edibles, concentrates, and oils to enhance your experience. Buy cannabis online at West Coast Cannabis Canada.

Frequently Asked Questions

Does cheap marijuana have poor quality?

No, price alone does not indicate product quality. You can assess quality by examining the product’s physical characteristics and testing it yourself. Some dispensaries offer lower prices through monthly or clearance sales. However, if a dispensary’s prices are significantly lower than industry standards, it may raise quality concerns.

Does marijuana cause any adverse effects when managing BPD?

No adverse side effects were reported by study participants using marijuana. This is significant for medication adherence, considering a review of 36 studies found that side effects contributed to 28% of patients’ non-adherence to antipsychotics. A negative attitude toward antipsychotic medications was the second most common reason for intentional non-adherence, at 30.5%.

What is the quickest way to experience the effects of cannabinoids for an EUPD problem?

Smoking, vaping, and dabbing are the fastest methods to experience cannabinoid effects. In the study, participants used vaping to consume dried flower. While smoking and vaping yield similar effects, the difference lies in inhaling smoke versus vapor. Dabbing, which involves concentrates, also provides a rapid onset of effects.

How many times can I smoke or vape to manage my symptoms?

The effectiveness of cannabis strains and products varies based on individual responses. In the study, patients adjusted their daily doses (between 0.5 and 2 grams) without exceeding monthly limits. For extracts, patients recorded their daily dosages.

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