West Coast Cannabis Canada has long valued cannabis, recognized by various names, for its diverse properties. A key characteristic of all cannabis plants is the presence of multiple substances called cannabinoids or phytocannabinoids.
Current biomechanics research into the therapeutic effects of these compounds is propelling the development of various applications for these plants, bringing hope to individuals seeking relief from their symptoms.
Let’s explore the components of the plant and discover options for accessing cannabis, should you wish to experience its potential benefits.
Table of Contents
Key Takeaways:
- The cannabis plant contains substances such as cannabinoids, terpenes, and flavonoids.
- When the compounds within cannabis interact harmoniously, it results in a fascinating phenomenon known as the entourage effect.
- Full-spectrum cannabis extracts may provide greater medical benefits compared to individual components of the plant.
The Cannabis Plants and Its Major Components
Cannabis, part of the Cannabaceae family alongside hops, is identified by the presence of secondary substances referred to as cannabinoids or phytocannabinoids. There are over 150 cannabinoids found alongside terpenoids, flavonoids, and alkaloids.
Cannabinoids
Cannabinoids are naturally occurring compounds primarily found in the flower buds of the cannabis plant. Known as phytocannabinoids due to their botanical origin, they significantly contribute to the plant’s composition. Among the numerous phytocannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most recognized and researched.
Terpenes
Terpenes are aromatic compounds that greatly influence the flavor and aroma of cannabis. They are not exclusive to cannabis; rather, they are found across nearly all plant life.
More than 140 terpenes have been identified within cannabis, each offering unique characteristics. Some terpenes are exclusive to cannabis and enhance its sensory profile. West Coast Cannabis Canada highlights B-myrcene as the most abundant terpene, followed by trans-caryophyllene and a-pinene.
Flavonoids
Flavonoids are natural compounds found in various plants, responsible for vibrant colors. In cannabis, flavonoids work alongside terpenes and cannabinoids, exhibiting anti-inflammatory and neuroprotective properties. Certain compounds, like apigenin, showcase anxiolytic and estrogenic traits, while cannaflavins A and B reveal potent anti-inflammatory capabilities.
Molecules Journal: Exploring the Combined Components of Cannabis and Its Impact on Therapeutic Benefits
According to an analysis by the advocacy group NORML, scientists have published over 32,000 marijuana studies in the past decade. While much of this research has focused on the effects of cannabis consumption, other components, such as cannabinoids, terpenes, and flavonoids, have often been overlooked. The literature heavily centers on the major cannabinoids THC and CBD.
The journal Molecules examines the interactions among the various chemical compounds found in marijuana. The emphasis is on understanding how these components work together, which is crucial for fully grasping the therapeutic potential of cannabis.
Understanding the Significance of the Endocannabinoid System
The endocannabinoid system (ECS) regulates numerous physiological processes within the nervous system. Dysregulation of the ECS is linked to various pathological conditions. Therapeutic interventions targeting ECS activity have shown promise in managing neuroinflammation-related medical issues. The ECS consists of a complex network of receptors, endocannabinoids derived from arachidonic acid, receptor ligands, and enzymes responsible for endocannabinoid metabolism.
The ECS, including endocannabinoids such as anandamide and 2-arachidonoylglycerol, as well as the enzymes involved in their production and degradation, along with cannabinoid receptors CB1 and CB2, represents one of the most widespread signaling systems within the brain. It influences various functions such as stress response, anxiety, memory, pain perception, and motivated behavior. Endocannabinoid signaling is vital for the ongoing development, maturation, and refinement of neural circuits during adolescence.
The Entourage Effect of Cannabis Components within the ECS
The entourage effect illustrates how interacting metabolites can modify the properties of individual molecules, regardless of their inherent pharmacological activity.
Preclinical research published in Molecules Journal (2019) and Oncotarget Journal (2020) highlights the interplay between phytocannabinoids and terpenes. These studies suggest that the potential therapeutic benefits of full-spectrum cannabis extracts may arise from what is termed the entourage effect.
Cannabinoids
Research from the British Journal of Pharmacology and Multiple Sclerosis and Related Disorders has noted the suppressive effects of a combination of THC and CBD on neuroinflammation in animal models of multiple sclerosis. Phytocannabinoids exhibit immunomodulatory and anti-inflammatory properties. For example, in LPS-activated microglial cells, THC and CBD showed distinct mechanisms of action, with THC regulating the IFNβ pathway and CBD inhibiting the NF-κB-dependent pathway.
Terpenes
Cheng et al. (2014) found that β-caryophyllene, a terpene, binds to CB2R receptors. This may contribute to the combined effects of various phytochemicals in C. sativa, aiding in alleviating neurotoxicity related to Alzheimer’s disease (AD).
Myrcene’s ability to enhance the transportation of delta-9-THC across the blood-brain barrier offers an intriguing pathway for developing AD therapeutics that can effectively reach the central nervous system.
Flavonoids
Flavonoids may help address oxidative stress and neurodegeneration, enhancing the neuroprotective effects associated with the entourage effect. A review in the journal Frontiers in Aging Neuroscience emphasized the neuroprotective benefits of various flavonoids, showing their capacity to mitigate neuroinflammation and reduce neurodegenerative mechanisms.
The Authors Take
Comprehending the complex interactions between cannabinoids, terpenes, and flavonoids is essential for realizing the full therapeutic benefits of cannabis, as highlighted by the authors in their study. They also identify crucial evidence gaps that need immediate attention.
- Investigating the synergistic effects and mechanisms of cannabinoids, terpenes, and flavonoids requires focused research.
- Understanding the complexities of cannabis phytochemical production and accumulation, especially under different lighting conditions, is vital for advancing medicinal applications.
- Thorough phytochemical characterization of cannabis strains, including their unique ratios of cannabinoids, terpenes, and flavonoids, can refine treatment strategies, leading to more personalized and effective medicinal interventions.
Where to Buy Weed?
If you’re interested in exploring the potential health benefits of cannabis but are unsure where to start, West Coast Cannabis Canada offers mail-order marijuana services and same-day cannabis delivery for convenient access to cannabis products. These platforms feature user-friendly websites that let you browse various marijuana products from home.
Purchasing cannabis online provides access to affordable options and promotional discounts, allowing you to find high-quality cannabis products tailored to your preferences.
Conclusion
Cannabis contains diverse compounds, each capable of unique effects. The synergy among these compounds enhances their therapeutic potential beyond initial expectations. Research, such as the study featured in the Molecules journal, offers valuable insights into the mechanisms of cannabis, emphasizing the importance of full-spectrum products for symptom management in specific conditions. While further targeted studies are necessary, preliminary findings offer promising glimpses into possibilities and understanding.
Frequently Asked Questions
How much does it cost to buy cannabis online in Canada?
The price of cannabis per gram is notably more affordable in Canada compared to the US. In physical dispensaries, a gram typically ranges from $10 to $12, while online dispensaries often start at $2 per gram. You can find cannabis online for around $5 per gram for satisfactory quality, generally within the AA+ to AAA grade range.
Can medical and recreational marijuana differ in price?
Both medical and recreational cannabis can be consumed, with medical cannabis often being less expensive. Medical cannabis expenses may qualify for tax deductions, and insurance coverage might be available to offset costs.
Are other marijuana products as affordable as cannabis flower?
The cost of buying cannabis online is generally more economical compared to traditional sources. Alternative products like edibles, capsules, and oils may have slightly higher prices, but they remain within reasonable limits. Online dispensaries strive to maintain competitive prices in the cannabis industry.
Is bulk cannabis cheaper than per gram?
Yes, purchasing cannabis in bulk can lead to discounts compared to per-gram purchases. This is particularly beneficial for frequent users or those using cannabis for medical reasons. Buying per gram allows you to experiment with its effects initially.
Does cheap cannabis mean low quality?
While price can influence the perception of cannabis quality, it is not the sole indicator. Inexpensive cannabis does not necessarily equate to inferior quality; it may reflect a batch nearing expiration, prompting dispensaries to offer it at a reduced price. Evaluating cannabis solely based on price may overlook the nuances contributing to its overall value and experience.
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